Head to https://linode.com/scishow to get a $100 60-day credit on a new Linode account. Linode offers simple, affordable, and accessible Linux cloud solutions and services.
In 2021, the FDA approved a treatment that claims to stop Alzheimer's at the source, removing the plaques in the brain long thought to cause the symptoms of the disease. But, as is often the case, things are more complicated than they first appear.
Hosted by: Michael Aranda
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Tomás Lagos González, Sam Lutfi. Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Jason A Saslow, Nazara, Tom Mosner, Ash, Eric Jensen, Jeffrey Mckishen, Matt Curls, Alex Hackman, Christopher R Boucher, Piya Shedden, Jeremy Mysliwiec, charles george, Chris Peters, Adam Brainard, Dr. Melvin Sanicas, Harrison Mills, Silas Emrys, Alisa Sherbow
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow
----------
Sources:
https://www.health.harvard.edu/blog/a-new-alzheimers-drug-has-been-approved-but-should-you-take-it-202106082483
https://www.fda.gov/news-events/press-announcements/fda-grants-accelerated-approval-alzheimers-drug
https://pubmed.ncbi.nlm.nih.gov/12130773/
https://www.statnews.com/2016/11/14/alzheimers-brain-amyloid-plaque/
https://www.science.org/doi/10.1126/science.1566067
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174086/
https://www.science.org/doi/pdf/10.1126/science.2933807
https://www.bmj.com/content/372/bmj.n156
https://www.nature.com/articles/d41586-021-01546-2
https://www.neurologylive.com/view/aducanumab-phase-4-real-world-observational-study-announced
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278466/
https://pubmed.ncbi.nlm.nih.gov/9189035/
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12213
https://www.orthopeden.org/downloads/242/Standardizing%20Patient%20Outcomes%20Measurement.pdf
https://jamanetwork.com/journals/jamaneurology/fullarticle/1107509
https://www.biopharma-reporter.com/Article/2021/12/20/Aducanumab-rejected-in-the-EU-Biogen-will-ask-EMA-to-re-examine-application
https://www.sciencedirect.com/topics/neuroscience/tau-protein
https://www.alz.org/media/Documents/alzheimers-dementia-tau-ts.pdf
https://pubmed.ncbi.nlm.nih.gov/9386780/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560290/
https://youtu.be/E6PgRD-CsYo?t=795
https://youtu.be/E6PgRD-CsYo?t=1908
https://youtu.be/E6PgRD-CsYo?t=625
https://www.brightfocus.org/alzheimers/article/tau-protein-and-alzheimers-disease-whats-connection
https://www.lexico.com/en/definition/glia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394397/
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(21)00067-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2162253121000676%3Fshowall%3Dtrue
https://www.alzheimersresearchuk.org/tackling-tau-scientists-find-local-spread-is-how-alzheimers-progresses/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713404/
https://www.jbc.org/article/S0021-9258(20)47639-2/fulltext
https://pubmed.ncbi.nlm.nih.gov/29053874/
Images:
https://commons.wikimedia.org/wiki/File:Amyloid_03big1.jpg
https://commons.wikimedia.org/wiki/File:Beta-Amyloid_Plaques_and_Tau_in_the_Brain_(38686503251).png
https://en.wikipedia.org/wiki/File:APP_processing.png
https://commons.wikimedia.org/wiki/File:Astrocytes_surrounding_amyloid_plaques_III.tif
https://commons.wikimedia.org/wiki/File:Alzheimers_Disease.jpg
https://commons.wikimedia.org/wiki/File:Entorhinal_-_DK_ATLAS.png
https://commons.wikimedia.org/wiki/File:Gray739-emphasizing-hippocampus.png
https://commons.wikimedia.org/wiki/File:Neurofibrillary_tangles_in_the_Hippocampus_of_an_old_person_with_Alzheimer-related_pathology,_HE_1.JPG
https://commons.wikimedia.org/wiki/File:Brain-derived_neurotrophic_factor_-_PDB_id_1BND.png
https://www.frontiersin.org/articles/10.3389/fnins.2019.01274/full
In 2021, the FDA approved a treatment that claims to stop Alzheimer's at the source, removing the plaques in the brain long thought to cause the symptoms of the disease. But, as is often the case, things are more complicated than they first appear.
Hosted by: Michael Aranda
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Tomás Lagos González, Sam Lutfi. Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Jason A Saslow, Nazara, Tom Mosner, Ash, Eric Jensen, Jeffrey Mckishen, Matt Curls, Alex Hackman, Christopher R Boucher, Piya Shedden, Jeremy Mysliwiec, charles george, Chris Peters, Adam Brainard, Dr. Melvin Sanicas, Harrison Mills, Silas Emrys, Alisa Sherbow
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow
----------
Sources:
https://www.health.harvard.edu/blog/a-new-alzheimers-drug-has-been-approved-but-should-you-take-it-202106082483
https://www.fda.gov/news-events/press-announcements/fda-grants-accelerated-approval-alzheimers-drug
https://pubmed.ncbi.nlm.nih.gov/12130773/
https://www.statnews.com/2016/11/14/alzheimers-brain-amyloid-plaque/
https://www.science.org/doi/10.1126/science.1566067
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174086/
https://www.science.org/doi/pdf/10.1126/science.2933807
https://www.bmj.com/content/372/bmj.n156
https://www.nature.com/articles/d41586-021-01546-2
https://www.neurologylive.com/view/aducanumab-phase-4-real-world-observational-study-announced
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278466/
https://pubmed.ncbi.nlm.nih.gov/9189035/
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12213
https://www.orthopeden.org/downloads/242/Standardizing%20Patient%20Outcomes%20Measurement.pdf
https://jamanetwork.com/journals/jamaneurology/fullarticle/1107509
https://www.biopharma-reporter.com/Article/2021/12/20/Aducanumab-rejected-in-the-EU-Biogen-will-ask-EMA-to-re-examine-application
https://www.sciencedirect.com/topics/neuroscience/tau-protein
https://www.alz.org/media/Documents/alzheimers-dementia-tau-ts.pdf
https://pubmed.ncbi.nlm.nih.gov/9386780/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560290/
https://youtu.be/E6PgRD-CsYo?t=795
https://youtu.be/E6PgRD-CsYo?t=1908
https://youtu.be/E6PgRD-CsYo?t=625
https://www.brightfocus.org/alzheimers/article/tau-protein-and-alzheimers-disease-whats-connection
https://www.lexico.com/en/definition/glia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394397/
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(21)00067-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2162253121000676%3Fshowall%3Dtrue
https://www.alzheimersresearchuk.org/tackling-tau-scientists-find-local-spread-is-how-alzheimers-progresses/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713404/
https://www.jbc.org/article/S0021-9258(20)47639-2/fulltext
https://pubmed.ncbi.nlm.nih.gov/29053874/
Images:
https://commons.wikimedia.org/wiki/File:Amyloid_03big1.jpg
https://commons.wikimedia.org/wiki/File:Beta-Amyloid_Plaques_and_Tau_in_the_Brain_(38686503251).png
https://en.wikipedia.org/wiki/File:APP_processing.png
https://commons.wikimedia.org/wiki/File:Astrocytes_surrounding_amyloid_plaques_III.tif
https://commons.wikimedia.org/wiki/File:Alzheimers_Disease.jpg
https://commons.wikimedia.org/wiki/File:Entorhinal_-_DK_ATLAS.png
https://commons.wikimedia.org/wiki/File:Gray739-emphasizing-hippocampus.png
https://commons.wikimedia.org/wiki/File:Neurofibrillary_tangles_in_the_Hippocampus_of_an_old_person_with_Alzheimer-related_pathology,_HE_1.JPG
https://commons.wikimedia.org/wiki/File:Brain-derived_neurotrophic_factor_-_PDB_id_1BND.png
https://www.frontiersin.org/articles/10.3389/fnins.2019.01274/full
- Category
- Documentary
- Tags
- SciShow, science, Hank
Be the first to comment