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Detecting Alzheimer's 20 years before onset

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Biomarkers for Alzheimer's disease begin to change many years before symptoms present and a diagnosis is made.

Shuheng Wang and Bote Zhao worked on a long term study tracking these changes. The team took samples from participants' cerebrospinal fluid, imaged their brain and carried out cognitive assessments over a 20 year period. They found one biomarker (amyloid-beta 42) began to differ, compared to participants who didn't go on to develop the disease, 18 years prior to diagnosis and many others would deviate in the years preceding. It's hoped these findings will lead to early diagnosis and intervention for those with Alzheimer's disease.

Read more about Alzheimer's disease https://www.nature.com/collections/adgggicdca

This Nature Video is editorially independent. It is produced with third party financial support. Read more about Supported Content here: https://partnerships.nature.com/commercial-content-at-nature-research/
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Documentary
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science, nature video, alzheimer's
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