Why Does COVID-19 Have So Many Symptoms?

SciShow is supported by Brilliant.org. Go to https://Brilliant.org/SciShow to get 20% off of an annual Premium subscription.

For a respiratory disease, COVID-19 sure seems to affect more than just the respiratory system. Scientists think the receptor ACE2 is to blame.

COVID-19 Playlist: https://www.youtube.com/playlist?list=PLsNB4peY6C6IQediwz2GzMTNvm_dMzr47

Hosted by: Olivia Gordon

SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:

Kevin Bealer, Jacob, Katie Marie Magnone, Charles Southerland, Eric Jensen, Christopher R Boucher, Alex Hackman, Matt Curls, Adam Brainard, Jeffrey McKishen, Scott Satovsky Jr, James Knight, Sam Buck, Chris Peters, Kevin Carpentier, Patrick D. Ashmore, Piya Shedden, Sam Lutfi, Charles George, Christoph Schwanke, Greg, Lehel Kovacs, Bd_Tmprd
----------
Looking for SciShow elsewhere on the internet?
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Tumblr: http://scishow.tumblr.com
Instagram: http://instagram.com/thescishow
----------
Sources:
https://www.healthline.com/health-news/the-covid-19-symptoms-most-people-could-miss
https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html
https://www.ncbi.nlm.nih.gov/books/NBK556152/
https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes
https://www.sciencedirect.com/science/article/pii/S128645791300155X
https://pubmed.ncbi.nlm.nih.gov/15869762/
https://journals.lww.com/shockjournal/FullText/2016/09000/Pulmonary_Angiotensin_Converting_Enzyme_2__ACE2_.3.aspx
https://fivethirtyeight.com/features/covid-19-is-a-respiratory-disease-so-why-is-it-affecting-patients-hearts-and-brains/
https://openoregon.pressbooks.pub/mhccmajorsbio/chapter/types-of-receptors/
https://academic.oup.com/cardiovascres/article/73/3/463/367423
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083867/
https://www.hindawi.com/journals/ijpep/2012/256294/
https://www.sciencedirect.com/science/article/pii/S128645791300155X
https://www.sciencedirect.com/science/article/pii/B9780128013649000250
https://www.uniprot.org/uniprot/P59594
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083867/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167588/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164637/pdf/367_1260.pdf
https://www.nature.com/articles/d41586-020-00502-w
https://www.nature.com/articles/s41591-020-0868-6
https://pubs.acs.org/doi/10.1021/acschemneuro.0c00210
https://neurosciencenews.com/olfaction-coronavirus-16368/
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30937-5/fulltext
https://immunology.sciencemag.org/content/5/47/eabc3582
https://www.authorea.com/users/311058/articles/441796-a-hypothesis-for-pathobiology-and-treatment-of-covid-19-the-centrality-of-ace1-ace2-imbalance
https://www.medrxiv.org/content/10.1101/2020.05.31.20114991v1
https://www.covid19hg.org/about/
https://www.statnews.com/2020/04/10/coronavirus-ace-2-receptor/
https://www.lowell.k12.ma.us/cms/lib/MA01907636/Centricity/Domain/4/Coronavirus%20Lowell%20Prevention%20Message.pdf
https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/q-a-coronaviruses
https://journals.lww.com/infectdis/fulltext/2007/01000/diarrhea_as_a_symptom_in_bacteremic_pneumococcal.9.aspx
https://theconversation.com/ace2-the-molecule-that-helps-coronavirus-invade-your-cells-138369
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102599/
https://science.sciencemag.org/content/367/6485/1444
https://theconversation.com/what-is-the-ace2-receptor-how-is-it-connected-to-coronavirus-and-why-might-it-be-key-to-treating-covid-19-the-experts-explain-136928
https://www.nature.com/articles/1002101
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864711/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107144
https://onlinelibrary.wiley.com/doi/abs/10.1002/ppul.20187
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473006/
https://jamanetwork.com/journals/jamacardiology/fullarticle/2763843
https://journals.lww.com/ajg/Documents/COVID19_Carvalho_et_al_AJG_Preproof.pdf

Image Sources:
https://www.videoblocks.com/video/blood-vessels-of-human-body-h1t2kysgrjymps8s7
https://www.videoblocks.com/video/lab-mouse-albino-walking-off-screen-hwc0thmlxixsje07i
https://bit.ly/3gxnxEe
https://bit.ly/3gGaDUp
https://www.istockphoto.com/photo/heart-human-heart-gm474242411-34878960
https://www.istockphoto.com/photo/the-doctors-take-care-of-covid-19-patient-gm1217942302-355713048
https://bit.ly/2O3xblQ
https://bit.ly/38PEdnX
https://www.istockphoto.com/photo/colon-gm168534047-17880478
https://www.videoblocks.com/video/scientist-working-with-petri-dishes-in-a-lab-sc7f7jtewj4q7akwp