Thalidomide is the infamous drug at the heart of one of the world's worst drug safety catastrophes in modern medicine. And yet, more recent research is finding that thalidomide is still worth using, despite the risks. So what makes this drug that causes life-altering fetal abnormalities such a good thing?
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Sources:
https://pubmed.ncbi.nlm.nih.gov/35771402/
https://journals.sagepub.com/doi/abs/10.1177/1078155220975825?journalCode=oppa
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631033/
Images:
https://commons.wikimedia.org/wiki/File:Pack_of_Thalidomide_tablets.jpg
https://www.gettyimages.com/detail/photo/closeup-pharmacist-hand-holding-medicine-box-royalty-free-image/897885148?phrase=pharmaceutical&adppopup=true
https://www.gettyimages.com/detail/photo/photo-of-the-fetus-on-an-ultrasound-scan-and-few-royalty-free-image/1297678794?adppopup=true
https://commons.wikimedia.org/wiki/File:NCP14053.jpg
https://www.gettyimages.com/detail/video/slow-motion-of-pipette-dripping-stock-footage/1405058944?adppopup=true
https://www.gettyimages.com/detail/photo/thalidomide-molecule-on-white-royalty-free-image/508726549?phrase=thalidomide&adppopup=true
https://www.gettyimages.com/detail/photo/spreading-royalty-free-image/172153877?phrase=hiv&adppopup=true
https://www.gettyimages.com/detail/photo/crohns-disease-royalty-free-image/912219418?phrase=Crohn%27s+disease&adppopup=true
https://commons.wikimedia.org/wiki/File:TNFa_Crystal_Structure.rsh.png
https://www.gettyimages.com/detail/photo/cell-attacking-a-cancer-cell-royalty-free-image/1383260152?phrase=cancer+cells+immune+system&adppopup=true
https://www.gettyimages.com/detail/illustration/step-of-angiogenesis-medical-learning-about-royalty-free-illustration/1370326138?phrase=angiogenesis&adppopup=true
https://www.gettyimages.com/detail/video/blood-cells-pulsing-down-artery-hd-stock-footage/883866318?adppopup=true
https://www.gettyimages.com/detail/video/hela-cells-in-culture-stock-footage/519856224?adppopup=true
https://www.gettyimages.com/detail/photo/cancer-malignant-cells-royalty-free-image/1372020529?phrase=cancer+treatment&adppopup=true
https://www.gettyimages.com/detail/illustration/multiple-myeloma-is-a-cancer-of-the-bone-royalty-free-illustration/881911948?phrase=myeloma&adppopup=true
https://www.gettyimages.com/detail/photo/senior-man-cant-remember-which-pill-to-take-royalty-free-image/1264979561?phrase=medication+mix+up&adppopup=true
https://www.gettyimages.com/detail/video/solving-the-test-exam-paper-choices-stock-footage/472947795?adppopup=true
https://www.gettyimages.com/detail/video/newborn-baby-and-little-hand-stock-footage/864018480?adppopup=true
https://www.gettyimages.com/detail/video/white-capsules-fall-from-a-metal-conveyor-automatic-line-stock-footage/1419962583?adppopup=true
Hosted by: Hank Green (he/him)
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer
----------
Looking for SciShow elsewhere on the internet?
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Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishowFacebook: http://www.facebook.com/scishow
#SciShow #science #education #learning #complexly
----------
Sources:
https://pubmed.ncbi.nlm.nih.gov/35771402/
https://journals.sagepub.com/doi/abs/10.1177/1078155220975825?journalCode=oppa
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540221/
https://www.dana-farber.org/newsroom/news-releases/2018/after-60-years--scientists-uncover-how-thalidomide-produced-birth-defects/
https://ar.iiarjournals.org/content/35/11/5767
https://www.accessdata.fda.gov/scripts/cder/rems/index.cfm?event=IndvRemsDetails.page&REMS=58
https://pubmed.ncbi.nlm.nih.gov/22348778/
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cereblon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737249/
https://pubmed.ncbi.nlm.nih.gov/32125404/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265446/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931443/
https://pubmed.ncbi.nlm.nih.gov/22650377/
https://thalomidrems.com
https://fda.report/media/86286/Thalomid--Patient-Guide.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362654/
https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt196563303
https://www.washingtonpost.com/archive/lifestyle/wellness/2000/01/04/thalidomides-legacy/c7bc3a6e-4c22-49b1-929d-0d117f085d0e/
https://www.washingtonpost.com/wp-srv/washtech/longterm/thalidomide/keystories/patient062089.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631033/
Images:
https://commons.wikimedia.org/wiki/File:Pack_of_Thalidomide_tablets.jpg
https://www.gettyimages.com/detail/photo/closeup-pharmacist-hand-holding-medicine-box-royalty-free-image/897885148?phrase=pharmaceutical&adppopup=true
https://www.gettyimages.com/detail/photo/photo-of-the-fetus-on-an-ultrasound-scan-and-few-royalty-free-image/1297678794?adppopup=true
https://commons.wikimedia.org/wiki/File:NCP14053.jpg
https://www.gettyimages.com/detail/video/slow-motion-of-pipette-dripping-stock-footage/1405058944?adppopup=true
https://www.gettyimages.com/detail/photo/thalidomide-molecule-on-white-royalty-free-image/508726549?phrase=thalidomide&adppopup=true
https://www.gettyimages.com/detail/photo/spreading-royalty-free-image/172153877?phrase=hiv&adppopup=true
https://www.gettyimages.com/detail/photo/crohns-disease-royalty-free-image/912219418?phrase=Crohn%27s+disease&adppopup=true
https://commons.wikimedia.org/wiki/File:TNFa_Crystal_Structure.rsh.png
https://www.gettyimages.com/detail/photo/cell-attacking-a-cancer-cell-royalty-free-image/1383260152?phrase=cancer+cells+immune+system&adppopup=true
https://www.gettyimages.com/detail/illustration/step-of-angiogenesis-medical-learning-about-royalty-free-illustration/1370326138?phrase=angiogenesis&adppopup=true
https://www.gettyimages.com/detail/video/blood-cells-pulsing-down-artery-hd-stock-footage/883866318?adppopup=true
https://www.gettyimages.com/detail/video/hela-cells-in-culture-stock-footage/519856224?adppopup=true
https://www.gettyimages.com/detail/photo/cancer-malignant-cells-royalty-free-image/1372020529?phrase=cancer+treatment&adppopup=true
https://www.gettyimages.com/detail/illustration/multiple-myeloma-is-a-cancer-of-the-bone-royalty-free-illustration/881911948?phrase=myeloma&adppopup=true
https://www.gettyimages.com/detail/photo/senior-man-cant-remember-which-pill-to-take-royalty-free-image/1264979561?phrase=medication+mix+up&adppopup=true
https://www.gettyimages.com/detail/video/solving-the-test-exam-paper-choices-stock-footage/472947795?adppopup=true
https://www.gettyimages.com/detail/video/newborn-baby-and-little-hand-stock-footage/864018480?adppopup=true
https://www.gettyimages.com/detail/video/white-capsules-fall-from-a-metal-conveyor-automatic-line-stock-footage/1419962583?adppopup=true
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