Happy 50th Birthday Guillermo!

Guillermo celebrated his 50th birthday today with love from around the globe, we take a look back at the first time he ever appeared on the show, and Jimmy talks about the annual doomsday clock, Dr. Fauci being the highest paid employee in the U.S. Government, a new anal swab COVID test being introduced in China, Joe Biden raising awareness for those reluctant to get the vaccine, Mike Pence’s awkward living situation, Ted Cruz wanting to “move on” from the events at the Capitol, and since Guillermo has given so many shots to so many of Hollywood’s biggest names throughout the years, we got some of his favorites together for a star-studded 50 shot salute in honor of his 50th birthday!

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Jimmy Kimmel serves as host and executive producer of Emmy®-nominated “Jimmy Kimmel Live!,” ABC’s late-night talk show. “Jimmy Kimmel Live!” is well known for its huge viral video successes, with over 11 billion views and more than 15 million subscribers on the show’s YouTube channel. Some of Kimmel’s most popular comedy bits include “Celebrities Read Mean Tweets,” “Lie Witness News,” “Unnecessary Censorship,” “Halloween Candy YouTube Challenge,” and music videos like “I (Wanna) Channing All Over Your Tatum.”