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Artificial embryos: the hidden steps in forming a spine

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Somitogenesis is the process by which segmented body structures like vertebrae form in embryos. While the process is well understood in animals like mice or zebrafish it is difficult to study in humans.

But now, researchers have created a model embryo capable of undergoing somitogenesis, using pluripotent stem cells; called an axioloid.

The researchers hope that this new platform will allow them to better study human development and the diseases that can arise when it is disrupted.

Read the paper: https://www.nature.com/articles/s41586-022-05649-2

For more stories like these sign up for the Nature Briefing: An essential round-up of science news, opinion and analysis, free in your inbox every weekday: https://go.nature.com/371OcVF
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