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Sometimes science surprises us with twists that we never could have predicted, and this is the case in the development of iPSCs.
Hosted by: Rose Bear Don't Walk (she/her)
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer
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Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow #science #education
----------
Sources:
https://pubmed.ncbi.nlm.nih.gov/16904174/
https://www.cell.com/cell/fulltext/S0092-8674(07)01471-7
https://link.springer.com/article/10.1007/s12015-021-10262-3
https://www.nature.com/scitable/definition/transcription-factor-167/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347549/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967385/
https://www.riken.jp/en/news_pubs/research_news/pr/2013/20130730_1/
https://www.nejm.org/doi/full/10.1056/NEJMoa1608368
https://pubmed.ncbi.nlm.nih.gov/29770269/
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/ful
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000082/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709242/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441954/
https://www.nature.com/articles/s41467-017-00236-w
https://journals.biologists.com/dev/article/144/11/1923/47944/Human-embryo-research-and-the-14-day-rule
https://www.nature.com/articles/s41467-021-23294-7
https://pubmed.ncbi.nlm.nih.gov/20813264/
https://www.sciencedirect.com/science/article/pii/S0093691X16300954
https://www.sciencedirect.com/science/article/pii/S1359644618301405
Image Sources:
https://commons.wikimedia.org/wiki/File:Human_induced_pluripotent_stem_cell_colony_(51816035910).jpg
https://commons.wikimedia.org/wiki/File:Efficient-and-Reproducible-Myogenic-Differentiation-from-Human-iPS-Cells-Prospects-for-Modeling-pone.0061540.s011.ogv
https://commons.wikimedia.org/wiki/File:Human_cheek_cell.jpg
https://www.gettyimages.com/detail/illustration/illustration-of-neuron-anatomy-vector-royalty-free-illustration/1153647071?phrase=neuron&adppopup=true
https://bit.ly/3hrzcKr
https://commons.wikimedia.org/wiki/File:Final_stem_cell_differentiation_(1).svg
https://commons.wikimedia.org/wiki/File:Shinya_yamanaka10.jpg
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/full
https://commons.wikimedia.org/wiki/File:Genetically-engineering-self-organization-of-human-pluripotent-stem-cells-into-a-liver-bud-like-ncomms10243-s2.ogv
https://commons.wikimedia.org/wiki/File:Human_embryonic_stem_cells_only_A.png
https://bit.ly/3NS6sqe
https://www.gettyimages.com/detail/illustration/macular-degeneration-vector-medical-scheme-royalty-free-illustration/963177108?phrase=macular%20degeneration&adppopup=true
https://commons.wikimedia.org/wiki/File:A-Novel-Serum-Free-Monolayer-Culture-for-Orderly-Hematopoietic-Differentiation-of-Human-Pluripotent-pone.0022261.s001.ogv
https://commons.wikimedia.org/wiki/File:How_iPSC_Works_(46181969695).jpg
https://www.gettyimages.com/detail/illustration/cell-engineering-and-cell-reprogramming-royalty-free-illustration/1429299555?phrase=ipsc&adppopup=true
https://commons.wikimedia.org/wiki/File:Working_with_induced_pluripotent_stem_cells_(46291373691).jpg
https://en.wikipedia.org/wiki/File:Humanstemcell.JPG
https://www.gettyimages.com/detail/illustration/human-embryo-genesis-by-weeks-vector-cartoon-royalty-free-illustration/1290299851?phrase=embryo&adppopup=true
https://www.gettyimages.com/detail/photo/home-caregiver-helping-a-senior-woman-standing-in-royalty-free-image/1397344064?phrase=parkinsons&adppopup=true
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/full
https://www.gettyimages.com/detail/photo/surgeon-with-organ-donation-royalty-free-image/160194832?phrase=organ%20transplant&adppopup=true
https://www.gettyimages.com/detail/photo/wistar-rat-on-a-metal-table-royalty-free-image/530921257?phrase=lab%20rat&adppopup=true
https://www.gettyimages.com/detail/photo/portrait-of-a-curious-little-piglet-looking-at-the-royalty-free-image/1367525280?phrase=pig&adppopup=true
https://commons.wikimedia.org/wiki/File:Yamanaka.jpg
https://commons.wikimedia.org/wiki/File:Induction_of_iPS_cells.svg
https://solarsystem.nasa.gov/missions/near-shoemaker/in-depth/
Sometimes science surprises us with twists that we never could have predicted, and this is the case in the development of iPSCs.
Hosted by: Rose Bear Don't Walk (she/her)
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow #science #education
----------
Sources:
https://pubmed.ncbi.nlm.nih.gov/16904174/
https://www.cell.com/cell/fulltext/S0092-8674(07)01471-7
https://link.springer.com/article/10.1007/s12015-021-10262-3
https://www.nature.com/scitable/definition/transcription-factor-167/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347549/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967385/
https://www.riken.jp/en/news_pubs/research_news/pr/2013/20130730_1/
https://www.nejm.org/doi/full/10.1056/NEJMoa1608368
https://pubmed.ncbi.nlm.nih.gov/29770269/
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/ful
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000082/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709242/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441954/
https://www.nature.com/articles/s41467-017-00236-w
https://journals.biologists.com/dev/article/144/11/1923/47944/Human-embryo-research-and-the-14-day-rule
https://www.nature.com/articles/s41467-021-23294-7
https://pubmed.ncbi.nlm.nih.gov/20813264/
https://www.sciencedirect.com/science/article/pii/S0093691X16300954
https://www.sciencedirect.com/science/article/pii/S1359644618301405
Image Sources:
https://commons.wikimedia.org/wiki/File:Human_induced_pluripotent_stem_cell_colony_(51816035910).jpg
https://commons.wikimedia.org/wiki/File:Efficient-and-Reproducible-Myogenic-Differentiation-from-Human-iPS-Cells-Prospects-for-Modeling-pone.0061540.s011.ogv
https://commons.wikimedia.org/wiki/File:Human_cheek_cell.jpg
https://www.gettyimages.com/detail/illustration/illustration-of-neuron-anatomy-vector-royalty-free-illustration/1153647071?phrase=neuron&adppopup=true
https://bit.ly/3hrzcKr
https://commons.wikimedia.org/wiki/File:Final_stem_cell_differentiation_(1).svg
https://commons.wikimedia.org/wiki/File:Shinya_yamanaka10.jpg
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/full
https://commons.wikimedia.org/wiki/File:Genetically-engineering-self-organization-of-human-pluripotent-stem-cells-into-a-liver-bud-like-ncomms10243-s2.ogv
https://commons.wikimedia.org/wiki/File:Human_embryonic_stem_cells_only_A.png
https://bit.ly/3NS6sqe
https://www.gettyimages.com/detail/illustration/macular-degeneration-vector-medical-scheme-royalty-free-illustration/963177108?phrase=macular%20degeneration&adppopup=true
https://commons.wikimedia.org/wiki/File:A-Novel-Serum-Free-Monolayer-Culture-for-Orderly-Hematopoietic-Differentiation-of-Human-Pluripotent-pone.0022261.s001.ogv
https://commons.wikimedia.org/wiki/File:How_iPSC_Works_(46181969695).jpg
https://www.gettyimages.com/detail/illustration/cell-engineering-and-cell-reprogramming-royalty-free-illustration/1429299555?phrase=ipsc&adppopup=true
https://commons.wikimedia.org/wiki/File:Working_with_induced_pluripotent_stem_cells_(46291373691).jpg
https://en.wikipedia.org/wiki/File:Humanstemcell.JPG
https://www.gettyimages.com/detail/illustration/human-embryo-genesis-by-weeks-vector-cartoon-royalty-free-illustration/1290299851?phrase=embryo&adppopup=true
https://www.gettyimages.com/detail/photo/home-caregiver-helping-a-senior-woman-standing-in-royalty-free-image/1397344064?phrase=parkinsons&adppopup=true
https://www.frontiersin.org/articles/10.3389/fcell.2015.00002/full
https://www.gettyimages.com/detail/photo/surgeon-with-organ-donation-royalty-free-image/160194832?phrase=organ%20transplant&adppopup=true
https://www.gettyimages.com/detail/photo/wistar-rat-on-a-metal-table-royalty-free-image/530921257?phrase=lab%20rat&adppopup=true
https://www.gettyimages.com/detail/photo/portrait-of-a-curious-little-piglet-looking-at-the-royalty-free-image/1367525280?phrase=pig&adppopup=true
https://commons.wikimedia.org/wiki/File:Yamanaka.jpg
https://commons.wikimedia.org/wiki/File:Induction_of_iPS_cells.svg
https://solarsystem.nasa.gov/missions/near-shoemaker/in-depth/
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